Frontier in Biofunction of Nucleic Acid and Organic Chemistry

Publication (2019-2022)


旧 Publicationsはこちら

  1. Notomi R., Sasaki S. andTaniguchi Y.*,
    Recognition of 5-Methyl-CG and CG Base Pairs in Duplex DNA with High Stability using Antiparallel-type Triplex-formingOligonucleotides with 2-Guanidinoethyl-2'-deoxy-nebularine,
    Nucleic Acids Res.,accepted. 
  2. Miyahara R. andTaniguchi Y.*
    Selective Unnatural Base Pairing and Recognition of 2-Hydroxy-2'-deoxyadenosine in DNA by Pseudo-dC Derivatives,
    J. Am. Chem. Soc.144 (35) 16150-16156 (2022)  DOI: https://doi.org/10.1021/jacs.2c07000
  3. Wu J., Zhang M., Song L., Tan Y.,Taniguchi Y., Hipolito C. J., Zhang Y. and Yin Y.*
    Implications of N7-hydrogen and C8-keto on the base pairing, mutagenic potential and repair of 8-oxo-2'-deoxy-adenosine:Investigation by nucleotide analogues,
    Bioorg. Chem.127, 106029 (2022)DOI:https://doi.org/10.1016/j.bioorg.2022.106029
  4. Togo N., Murase H., Lee J.,Taniguchi Y. and Sasaki S.*
    Application of the Functionality Transfer Oligonucleotide for the Site-Selective Modification of RNA with a Divers Molecule,
    Chem. Pharm. Bull.70 (7), 498-504 (2022)DOI:https://doi.org/10.1248/cpb.c22-00288
  5. Kikukawa Y., Kawazoe R., Miyahara R., Sakurada T., Nagata Y., Sasaki S. andTaniguchi Y.*
    Multiple-turnover single nucleotide primer extension reactions to detect of 8-oxo-2'-deoxyguanosine,  
    ChemComm.58 (35), 5399-5402 (2022)DOI: 10.1039/d2cc01372j
  6. Taniguchi Y.*
    Development of Artificial Nucleoside Analogues for the Recognition and Detection of Damaged Nucleoside in DNA,
    J. Syn. Org. Chem.80 (1), 46-54 (2022)DOI: https://doi.org/10.5059/yukigoseikyokaishi.80.46
  7. Yamauchi K., Matsuoka Y., Takahashi M., Yoshihiro N.,Taniguchi Y., Kawai K., Bamba T. and Yamada K.*
    Detection and Structural Analysis of Pyrimidine-Derivatived Radicals Generated on DNA using a Profluorescent NitroxideProbe,
    ChemComm.58 (1), 56-59 (2022)Doi:https://doi.org/10.1039/D1CC04998D 

      
           J. Am. Chem. Soc.                            Bioorg. Chem.                    Chem. Pharm. Bull.
     
         ChemComm                                                 ChemComm

  8. Sakurada T., Miyahara R., Kawazoe R., Nagata Y., Kikukawa Y., Sasaki S. and  Taniguchi Y.* 
    Simple and easy synthesis of g-amido-dNTPs in water and their polymerase reaction properties,  
    Chem. Pharm. Bull.69(11), 1061-1066 (2021)Doi: https://doi.org/10.1248/cpb.c21-00497 
  9. Notomi R., Wang L., Sasaki S. and  Taniguchi Y.* 
    Design and synthesis of purine nucleoside analogues for the formation of stable anti-parallel-type triplex DNA withduplex DNAbearing the5mCG base pair,
    RSC Adv. 11,21390-21396 (2021)Doi: 10.1039/D1RA02831F
  10. Shi H., Ishikawa R., Heh C.H., Sasaki S. and  Taniguchi Y.* 
    Development of MTH1-binding nucleotide analogs based on 7,8-dihalogenated 7-deaza-dG derivatives,
    Int. J. Mol. Sci. 22(3),1274 (2021)  Doi: org/10.3390/ijms22031274


  11. Notomi R., Wang L., Osuki T., Okamiura H., Sasaki S.* and  Taniguchi Y.*
    Synthesis of C-nucleoside analogues based on the pyrimidine skeleton for the formation of anti-parallel-type triplex DNA witha CG mismatch site,
    Bioorg. Med. Chem.28(23), 115782 (2020)https://doi.org/10.1016/j.bmc.2020.115782
  12. Kikuta K., Barta J.,Taniguchi Y.and Sasaki S.*
    Synthesis of Nucleotide Derivatives of N-Acyl-7-Nitroindoline, their Incorporation into the DNA Oligomer, and Evaluation ofTheir Photoreactivity in the DNA/RNA duplex,
    Chem. Pharm. Bull.68(12), 1210-1219 (2020)https://doi.org/10.1248/cpb.c20-00594
  13. Wang L., Okamiura H., Sasaki S.* andTaniguchi Y.*
    Enhancements in the Utilization of Antigene Oligonucleotides in the Nucleus by Booster Oligonucleotides,
    ChemComm., 56(67), 9731-9734 (2020) https://doi.org/10.1039/D0CC04240D 
  14. Taniguchi Y.*, Magata Y., Osuki T., Notomi R., Wang L., Okamiura H. and Sasaki S.*
    Development of novel C-nucleoside analogues for formation of antiparallel-type triplex DNA with DNA that includes TA and dUAbase pairs,Org. Biomol. Chem.,18 (15), 2845-2851 (2020) https://doi.org/10.1039/D0OB00420K
  15. Aoki Y.*,Taniguchi Y., Matsumoto M., Matsumoto M., Ohno M., Masumura K., Sasaki S., Tsuzuki T., Yamamoto M.,Nohmi T.
    Oxidative stress driven mutagenesis in the small intestine of the gpt delta mouse induced by oral administration of potassiumbromate,
    Mutation Research - Genetic Toxicology and Environmental Mutagenesis. (Mutat Res Gen Tox En)  850-851, 503136(p1-9) (2020)  https://doi.org/10.1016/j.mrgentox.2020.503136

           
             Chem.Comm.
           
             Org. Biomol. Chem.            Mutat Res Gen Tox En

  16. Taniguchi Y.*, Cao X., Sasaki S.*
    Synthesis of  the deuterated thymidine-d9 and deuterated oligonucleotides,
    Tetrahedron Letters.60(38) 151037-151039 (2019)  DOI:https://doi.org/10.1016/j.tetlet.2019.151037
  17. Taniguchi Y.*, Sagara I., Nagata Y., Kikukawa Y., Sasaki S.*
    Effect of the 2-substituted adenosine-1,3-diazaphenoxazine 5'-triphosphate derivatives on the single primer extension reactionby DNA polymerase,
    Chem. Pharm. Bull.67(10), 1123-1130 (2019)DOI:https://doi.org/10.1248/cpb.c19-00453
  18. Kikuta K.,Taniguchi Y., Sasaki S.*
    Study of the inducible cross-linking reaction to mRNA and the effect on the translation,
    Chem. Pharm. Bull.67(8), 877-883  (2019)DOI:https://doi.org/10.1248/cpb.c19-00337
  19. Thavoncharoensub N., Maruyama K., Heh C.H., Leong K.H., Shi H., Shigematsu Y., Sasaki S. andTaniguchi Y.*
    Synthesis of  g-N-modified 8-oxo-2'-deoxyguanosine triphosphate and its characterization,
    Nucleosides, Nucleotides and Nucleic Acids.38(8), 578-589 (2019) https://doi.org/10.1080/15257770.2019.1586919 
  20. Taniguchi Y.*,Wang L., Okamura H. and Sasaki S.*
    Synthesis of 2'-deoxy-4-aminopyridinylpseudocytidine derivatives for incorporation into triplex forming oligonucleotides,
    Current Protocoles in Nucleic Acids Chemistry.  77(1), e80 (2019)DOI: https://doi.org/10.1002/cpnc.80